Open AccessLipid Profile Evaluation in Second and Third Trimester of Pregnancy and Fetomaternal Outcome
Author(s) -
Neeraj Sharma,
Jaswant Raj,
Neha Seehra
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v69i01.017
Subject(s) - medicine , pregnancy , dyslipidemia , lipid profile , preeclampsia , obstetrics , fetus , gestational age , population , subclinical infection , gestational hypertension , birth weight , gestation , prospective cohort study , small for gestational age , gynecology , obesity , cholesterol , endocrinology , biology , genetics , environmental health
Increase in maternal cholesterol levels are thought to be an adaptive change necessary for proper fetal development and growth. However maternal dyslipedemia has been shown to be associated with complications during pregnancy. Objective of this study is evaluation of changes in lipid profile during pregnancy and their association with fetomaternal outcome. It was a prospectivedescriptive study conducted over 200 pregnant women from December 2018 to August 2020 at jay kaylon hospital, kota, Rajasthan. 3 ml serum samples of enrolled pregnant women and 100 non pregnant women were obtained for the estimation of serum lipid profile by ERBA manheim EM360 auto analyzer. 56% women belonged to the age group of 21-25 years, 70% patients were from urban population, 63.5% women had vegetarian diet, 49.5% were primigravida. Statistically significant rise found in the lipid profile values (p 2.5 kilogram. Pregnancy furnishes a unique opportunity for detection of subclinical dyslipidemia, significant increase has been found in the lipid profile when compared to non-pregnant women. However higher lipid levels have shown to be associated with gestational hypertension, preeclampsia and their complications along with low birth weight. Hence, we recommend lipid profile evaluation should be a part of routine antenatal investigations for early detection and management of these complications.