Open AccessBasic Review: Solubility Enhancement by Using Various Approaches
Author(s) -
Baldha Krunal,
Sanjay Savaliya,
Payal N Vaja,
Chetan H Borkhtaria
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v68i02.026
Subject(s) - bioavailability , solubility , biochemical engineering , drug , site of action , chemistry , process (computing) , pharmacology , nanotechnology , computer science , materials science , medicine , organic chemistry , engineering , operating system
The solubility enhancement process of drugs plays a key role in the formulation development to achieve the bioavailability and therapeutic action of the drug at the target site. About 40% of the new chemical entities identified by pharmaceutical industry screening programs face numerous problems in the formulation and development stage because of poor water solubility and low bioavailability. Drug solubility and bioavailability enhancement are theimportant challenges in the field of formulation of pharmaceuticals.