Open AccessGC-MS Analysis and Antimicrobial Activities of Ethanol Alkaloid Leaf Extracts of Delonix elata.L
Author(s) -
D. Muthuselvam,
Kathick Kathick
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v68i02.016
Subject(s) - antimicrobial , traditional medicine , phytochemical , candida albicans , alkaloid , biology , staphylococcus aureus , agar diffusion test , aspergillus niger , microbiology and biotechnology , botany , bacteria , medicine , food science , genetics
Delonix elata L., belongs to family Fabaceae used by the traditional various medicinal practices to cure jaundice, skin disease, heartdisease, cancer cell formation, physiological abnormalities, heptoprotective, bronchial and rheumatic problems. The present study was screen the antimicrobial and phytochemical activity of alkaloid leaf extracts. This extracts was assessed on multidrug resistant clinical isolated from both gram positive, gram negative and antifungal strains including Bacillus subtilis, Staphylococcus aureus, Escherchia coli, Pseudomonas aeruginosa, Candida albicans and Aspergillus niger. The zone of inhibition was determined by Agar well diffusion method with various concentration. GC- MS analysis was performed to identify major bioactive compounds present in the extracts. The GC – MS studies shown the present of 25 compound were identified in the leaf extract composition. The antimicrobial analysis revealed that C. albicans showed a highest zone of inhibition 25mm at 100 mg/ml of extracts. Present finding suggest that D. elata as plant pharmaceutical and pharmacological importance.