Open AccessA Review on Management of Antibiotic Resistance: A Slow and Progressive Pandemic
Author(s) -
Devesh Kumar Mishra,
Alok Kumar Shukla,
Vivek Srivastava
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v68i02.015
Subject(s) - antibiotics , antibiotic resistance , organism , resistance (ecology) , biology , pandemic , intensive care medicine , microbiology and biotechnology , disease , medicine , genetics , covid-19 , infectious disease (medical specialty) , ecology , pathology
Resistance in microbes against antibiotics is a slow but a constant process which can occurs via different modes according to the typeand strain of the particular organism; from one species to other thus influencing selection of antibiotic to treat the infection, resulting into exposure of variety of antibiotics providing a competitive advantage for mutated as well as non-mutated strains. Resistance in microbes against antibiotics can occurs via different modes depending upon the type and strain of that particular organism. In certain types of microorganism natural resistance can be found which was present before the discovery of antibiotics; certain types of microbes undergo genetic mutations over the time and hence develop resistance also some of them have been evolved as superbugs. Antibiotics Resistance is a continuous process from one species to other thus influencing selection of antibiotic to treat the infection, resulting into exposure of variety of antibiotics providing a competitive advantage for mutated as well as non-mutated strains. World Health Organization has taken several steps to avoid resistance chances. In this review an attempt has been made to figure out this alarming threat about antibiotic resistance, how can we preserve the antibiotics which are still non-resistance and ideal approaches to manage those disease which have been already reported to resistance to many of the available antibiotics. Medical professionals across the globe should follow the good practices while prescribing antibiotics, following the guidelines by WHO. Though in tough time several initiatives have been made between government, public and private sectors for the development of newer antibiotics.