Open AccessComputer Aided Drug Screening for Lung Infection
Author(s) -
Joydeep Paul,
Payel Debnath,
Ranajit Nath,
Ratul Bhowmik,
Sara Farheen
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v68i01.027
Subject(s) - medicine , drug , baicalein , lung , cause of death , clinical trial , disease , pharmacology
Lung infections are the leading cause of morbidity and mortality worldwide. Most causes of infection are not treatable. In childrenless than 5 years of age, they are the cause of death. Most infections are caused by viruses and bacteria. We present a dockingscreening using a quantum mechanical scoring of a library built from approved drugs and competent that apiin, baicalein, boswellic acid, eugenol, ganoderic acid, quercetin, vasicine, with proteins with PDB id’s 1VQQ, 3N26, 7K40, 5EG7 could display antiviral activity against lung infection. Clearly, these compounds should be further evaluated and clinical trials to confirm their actual activity against the disease