Open AccessNiosomes as a Potential Drug Delivery System
Author(s) -
Pratiksha Aher,
Kamlesh Dandgavhal,
Deepali Bhandari,
Harshata Saindane,
Nita Deore,
Sunil V. Amrutkar
Publication year - 2021
Publication title -
international journal of pharmaceutical sciences review and research
Language(s) - English
Resource type - Journals
ISSN - 0976-044X
DOI - 10.47583/ijpsrr.2021.v68i01.004
Subject(s) - niosome , sonication , drug delivery , pulmonary surfactant , liposome , nanotechnology , vesicle , drug carrier , pharmacology , materials science , chemistry , medicine , membrane , chromatography , chemical engineering , engineering , biochemistry
A non-ionic vesicle dependent on surfactants is a niosome. Niosomes are mainly formed as an excipient by non-ionic surfactant and cholesterol incorporation. Various excipients can also be used. Niosomes have a greater penetrating potential than previous emulsion preparations. There are various methods of manufacturing niosomes like thin film hydration, microfluidization, sonication, bubble method to name a few. The fact that niosomes are amphiphillic molecules makes them a flexible carrier of drugs, as both hydrophilic and lipophillic drugs can be trapped. Applications of niosomes in the pharmaceutical industry are many, some of the most important ones being as cosmoceuticals, gene delivery carriers, carriers for vaccine delivery and also in medical imaging. The main object of this review the appliance of niosome technology is employed to treat variety of diseases, niosome have good opportunity in research and beneficial for researcher and pharma industries. As niosome is stable and economical, niosome seems to be a well-preferred drug delivery mechanism over liposome.