Open AccessFrequency of occurrence of genetic polymorphisms associated with sports success in elite athletes in team sports
Author(s) -
E. I. Sorokina,
Н. Н. Денисова,
Э. Э. Кешабянц
Publication year - 2021
Publication title -
sportivnaâ medicina: nauka i praktika
Language(s) - English
Resource type - Journals
eISSN - 2587-9014
pISSN - 2223-2524
DOI - 10.47529/2223-2524.2021.1.11
Subject(s) - allele , genotyping , genetics , allele frequency , genotype , polymorphism (computer science) , gene polymorphism , biology , gene , athletes , medicine , physical therapy
Objective: to evaluate the frequency of occurrence of polymorphisms rs1815739 (ACTN3 gene), rs2016520 (PPARD gene), rs1042713 (ADRB2 gene), rs1799945 (HFE gene) in athletes of highperformance sports. Materials and methods: genotyping was performed using allelespecific amplification with realtime detection of the results and using TaqMan probes. Results: a higher frequency of alleles associated with endurance was found: the t allele of the rs1815739 polymorphism (ACTN3 gene), the g allele of the rs2016520 polymorphism (PPARD gene), the g allele of the rs1042713 polymorphism (ADRB2 gene), and the g allele of the rs1799945 polymorphism (HFE gene) in athletes of game sports. Conclusion: the results of genotyping of polymorphisms associated with endurance in the examined athletes showed a higher frequency of occurrence than in the population as a whole.