Open AccessAntioxidant and Radical Scavenging of Piliostigma reticulatum using FRAP and DPPH
Author(s) -
Taye Temikotan,
Mr Omotayo
Publication year - 2021
Publication title -
journal of pharmaceutical research and development
Language(s) - English
Resource type - Journals
ISSN - 2694-5614
DOI - 10.47485/2694-5614.1010
Subject(s) - dpph , chemistry , phytochemical , saponin , ethyl acetate , traditional medicine , antibacterial activity , antioxidant , anthraquinones , food science , phenols , organic chemistry , botany , biochemistry , biology , bacteria , medicine , alternative medicine , pathology , genetics
The antibacterial activity, phytochemical constituents and the radical scavenging ability using FRAP and DPPH of Piliostigma reticulatum were investigated in this study. Of all the solvent extracts used to assay the antibacterial effect, ethanol extract had the highest activity, followed by the aqueous extract with very weak activity against Pseudomonsa aeruginosa, Salmonella typhi and E. coli, methanol extract had no visible effect on the test organisms while ethyl acetate was active against only E. coli. The presence of phytochemicals such as alkaloids, glycosides, steroids, anthraquinones, phenol, tanin and saponin was observed. Antinutrients such as Tanin, Phenol, Phylate, Oxalate, Saponin and Flavonoids in copious amount. Ethanol extract of P. reticulatum was found to have the highest antioxidant ability, followed by the methanol extract. Ehtyl acetate extract had minimal radical scavenging ability. The antibacterial effect, phytochemical content and the radical scavenging properties of the plant makes it a good candidate in the development of antimicrobial therapeutics.