Open AccessBiological effects of oxygen-enriched drinking water. Review. Part 2
Author(s) -
Jurii A. Rakhmanin,
Natalija A. Egorova,
Rufina I. Mihajlova,
Iri. Ryzhova,
Marina G. Kochetkova
Publication year - 2021
Publication title -
gigiena i sanitariâ
Language(s) - English
Resource type - Journals
eISSN - 2412-0650
pISSN - 0016-9900
DOI - 10.47470/0016-9900-2021-100-1-25-29
Subject(s) - hypoxia (environmental) , oxygen , oxygen therapy , medicine , physiology , chemistry , organic chemistry
Human life on Earth depends on the continuous availability of oxygen. Conditions for the entry of oxygen into the body’s cells change in time and space, are easily broken, thus causing the possibility of development of hypoxia - a condition of oxygen starvation of tissues. The second part of the review is devoted to information about the successful use of oxygen-rich water in domestic therapeutic and surgical practice in complex treatment to reduce the negative effect of hypoxia in patients with chronic heart failure and generalized peritonitis complicated by intestinal insufficiency syndrome. Authors consider a common method for improving the supply of oxygen to the body using enteral oxygen therapy - oxygen cocktails in diseases of the cardiovascular system, lungs, bronchi and gastrointestinal tract, atopic dermatitis, placental insufficiency, as well as to improve physical performance, reduce the level of neuroticism and normalize the psychoemotional status. The first part of the review provides data on the modern understanding processes providing oxygen homeostasis in cells, on the critical component responsible for regulating the molecular response to hypoxia - the Hypoxia-Inducible Factors (HIFs) of the family of transcription factors. The possibility to compensate for the lack of oxygen in the body by delivering it to cells and tissues was indicated to consider water and various oxygen cocktails. Data from experimental studies of the biological effect of oxygenated drinking water are analyzed, as well as the results of studying the effects of oxygen-enriched drinking water with the participation of volunteers. The issue of the formation of oxygen (free) radicals when drinking oxygen-enriched drinking water is considered. The review draws specialist’s attention to the problem of the biological effect of oxygen-enriched drinking water, its insufficient knowledge and the possible yet unrealized potential in terms of preventing various diseases and maintaining optimal human health.