Open AccessGeneralized sarcoidosis and severe thrombocytopenic purpura: clinical observation and literature review
Author(s) -
L. A. Ponomareva,
AUTHOR_ID,
L.A. Panchenko,
A. B. Ponomarev,
Е Н Попова,
Yu.V. Putincev,
AUTHOR_ID,
AUTHOR_ID,
AUTHOR_ID,
AUTHOR_ID
Publication year - 2020
Publication title -
kliničeskij razbor v obŝej medicine
Language(s) - English
Resource type - Journals
eISSN - 2782-5671
pISSN - 2713-2552
DOI - 10.47407/kr2020.1.2.00011
Subject(s) - sarcoidosis , medicine , thrombocytopenic purpura , immunology , etiology , pancytopenia , disease , systemic disease , purpura (gastropod) , dermatology , pathology , platelet , immunopathology , bone marrow , ecology , biology
Sarcoidosis is a disease of an unknown etiology and is characterized by a wide range of clinical manifestations due to granulomatous damage of the lungs and other organs. Hematologic disorders in sarcoidosis are represented by different variants of pancytopenia, while autoimmune thrombocytopenic purpura is rare. Hemorrhagic syndrome with critical thrombocytopenia in blood of a patient with systemic sarcoidosis (damage to the lungs, nervous system, skin) coincided with an episode of a viral infection with symptoms of COVID-19 and the detection of an increased titer of antibodies to SARS-CoV-2 in the blood. In our paper we described the clinical features of the disease, medical treatment. The issues of managing patients with sarcoidosis during a pandemic time are discussed.