Open AccessChildhood Myelodysplastic Syndrome: A Rare Entity
Author(s) -
Mavra Fatima
Publication year - 2022
Publication title -
journal of diagnosis and case reports
Language(s) - English
Resource type - Journals
ISSN - 2754-4923
DOI - 10.47363/jdcrs/2022(3)127
Subject(s) - cytopenia , myelodysplastic syndromes , medicine , pediatrics , dysplasia , aplastic anemia , bone marrow failure , pancytopenia , refractory anemia , bone marrow , anemia , stem cell , haematopoiesis , biology , genetics
Myelodysplastic syndrome (MDS) is a spectrum of bone marrow disorders resulting from clonal stem cell defect that manifest as cytopenias, ineffective hematopoiesis and dysplasia in all the three cell lines. Myelodysplastic syndrome is rare in children and accounts for less than 5% of the hematopoieitic malignancies below the age of 14 years. Refractory cytopenia of childhood (RCC) is the most common type of MDS that is seen in children. In this study, we report a case of 14 years old boy who presented to us with suspicion of aplastic anemia and was diagnosed as refractory cytopenia of childhood, a type of myelodysplastic syndrome.