Open AccessSelected Landmark Studies in the Role of the Mesolimbic System
Author(s) -
Prakul Suresh,
Basil M. Baccouche
Publication year - 2021
Publication title -
journal of cardiology research reviews and reports
Language(s) - English
Resource type - Journals
ISSN - 2634-6796
DOI - 10.47363/jcrrr/2021(3)144
Subject(s) - landmark , mechanism (biology) , chronic pain , psychology , feeling , reward system , globe , perception , neuroscience , social psychology , computer science , artificial intelligence , philosophy , epistemology
The mesolimbic system has been demonstrated to have a major role in the perception of pain, but the mechanisms by which this occurs are poorly understood. In this paper, we review selected landmark studies that have contributed to our present understanding of the role of the mesolimbic system. The included studies outline the molecular mechanisms of the mesolimbic system's role in analgesia, pain relief, and feelings of decreased motivation and depression as a result of chronic pain. Because chronic pain is among the most highly-cited reasons for decreased quality of life, advancing our understanding of the function and mechanism of the mesolimbic system may be critical to improving the quality of life for millions of people around the globe