Open AccessCytokine Storm Syndrome in Covid-19 Patients: Characteristics and Diagnosis
Author(s) -
Rim Harfouch,
AUTHOR_ID
Publication year - 2021
Publication title -
journal of clinical epidemiology and toxicology
Language(s) - English
Resource type - Journals
ISSN - 2754-4974
DOI - 10.47363/jcet/2021(2)121
Subject(s) - cytokine storm , cytokine , medicine , covid-19 , pandemic , inflammation , immunology , cytokine release syndrome , storm , disease , infectious disease (medical specialty) , meteorology , physics
Cytokine storm syndrome (CSS) is a critical condition induced by a cascade of cytokine activation, characterized by overwhelming systemic inflammation, hyperferritinaemia, haemodynamic instability and multiple organ failure. At the end of 2019, the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, and rapidly developed into a global pandemic. There is a dramatic increase of inflammatory cytokines in patients with COVID-19, suggesting the existence of cytokine storm in some critical illness patients. Here, we summarize the p