Open AccessGuillain-Barré Syndrome After Receiving Sputnik Light COVID-19 Vaccine: A Case Report form Palestine
Author(s) -
Hamdoon AbuArish,
Abdelwadod Abuturki
Publication year - 2022
Language(s) - English
DOI - 10.47363/jccsr/2021(4)199
Subject(s) - guillain barre syndrome , medicine , vaccination , molecular mimicry , pediatrics , covid-19 , medical history , magnetic resonance imaging , paralysis , intensive care medicine , virology , immunology , pathology , surgery , antibody , radiology , disease , infectious disease (medical specialty)
We present this case of a 50-year-old man with no previous history of COVID-19 infection or recent viral or bacterial infections who presented as a case of Guillain-Barre syndrome 10 days after he received the COVID-19 vaccination. The diagnosis has been made on the basis of physical examination, magnetic resonance imaging (MRI) of the spine, cerebrospinal fluid (CSF) analysis, and electromyography (EMG). The reported cases of GBS following vaccination supported the theory of molecular mimicry as an underlying pathophysiology for this disorder. However, research has not yet identified the exact mechanism at the molecular level. In the best of our knowledge, this is the first case from Palestine to be reported. We hope that our report will encourage further research on this issue and warn medical professionals to consider GBS as a possible diagnosis in patients who present with acute flaccid paralysis (AFP) after vaccination with COVID19.