Open AccessEpidemiological and Clinical factors associated with mortality of confirmed Covid-19 cases admitted and treated in a tertiary care hospital of Patna, Bihar
Author(s) -
Alok Ranjan,
Sanjay Kumar Pandey,
Chandramani Singh,
Pragya Kumar,
Arshad Ayub,
Lokesh Tiwari,
Sanjeev Kumar,
Parul Singh
Publication year - 2021
Publication title -
indian journal of community health/indian journal of community health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.149
H-Index - 9
eISSN - 2248-9509
pISSN - 0971-7587
DOI - 10.47203/ijch.2021.v33i01.005
Subject(s) - medicine , epidemiology , case fatality rate , odds ratio , confounding , incidence (geometry) , population , mortality rate , pediatrics , cross sectional study , demography , pathology , environmental health , physics , sociology , optics
Background: A significant proportion of the individuals having the illness of moderate to severe nature due to COVID-19 infection require immediate critical care. High incidence of mortality among elderly population or those with comorbid conditions were reported. Objectives: The study was carried out with objectives to assess the epidemiological and clinical factors associated with mortality among the COVID-19 cases admitted and treated in AIIMS, Patna. Methods: This was a hospital‑based cross‑sectional analytical study of epidemiological and clinical features of COVID‑19‑positive patients admitted and treated during the outbreak from March 20, to August 31, 2020. Results: The median age of COVID-19 cases was 51.5 years (IQR : 37-62 years) which was significantly higher (p-value = 0.001) as compared to females. Male-female ratio of cases was 2.88:1. Out of 1696 cases, the case-fatality rate was 309 (18.22%). The mean age of cases who died due to COVID-19 was significantly higher (p-value=0.001) as compared to those who survived. The odds of mortality was significantly higher in males as compared to females (Adjusted OR = 1.534, 95% CI = 1.10 – 2.13, p=0.011). The odds of mortality showed a significant increasing trend with increasing age (Mantel-Hanszel p-value for trend = 0.015). The covariates like gender, age groups 45-59, 60-74 and 75>=, breathlessness and CKD were found to be significantly associated with mortality after controlling for the confounders. Conclusions: Factors like gender, higher age, lower oxygen saturation causing breathlessness and chronic kidney diseases could be attributed to high risk of mortality in COVID-19 patients.