Open AccessHPLC Profile of Phenolic Contents, Antioxidant and Antidiabetic Activities of Methanolic Extract of the Leaves of Sarcocephalus latifolius(Bruce, Smith) Grown in North Central Geopolitical Zone, Nigeria
Author(s) -
Adeyinka Elizabeth Ajiboye,
Olayinka T. Asekun,
Oluwole B. Familoni
Publication year - 2020
Publication title -
jordan journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2079-7249
pISSN - 1814-9111
DOI - 10.47014/15.3.1
Subject(s) - phytochemical , chemistry , phenols , quercetin , antioxidant , glycoside , high performance liquid chromatography , amentoflavone , catechin , traditional medicine , polyphenol , fraction (chemistry) , food science , chromatography , organic chemistry , biochemistry , medicine
Preliminary phytochemical screening of the n-butanol fraction of the methanol leaf extract of Sarcocephalus latifoliuswas carried out;its phenolic contents were quantified by HPLC. The in vitroantihyperglycemic and antioxidant activities of the fraction were evaluated.The results of the present study indicated that the leaves’extract contained phytochemicals,like phenols, flavonoids, alkaloids and glycosides.Phenolic compounds,such as garlic acid, catechin, ferrulic acid, p-coumaric acid, apigen-7-glucose, kaemferol, quercetin and amentoflavone,were quantified by HPLC. Moreover, the fraction of leaves’extract of S.latifoliusdemonstrated significant antioxidant and antihyperglyce-mic activities.The presence of these phytochemicals,especially phenols and flavonoids,in the leavesof S.latifoliustherefore justifiesitsmedicinal usefulness,as this plant has the potential to protect oxidative stress-induced ailments