Assessment of Inﬂammatory Markers IL- 6 and TNF- Alpha in Newly Diagnosed Type II Diabetics without Hypertension in Comparison with Non-Diabetic Normotensive Subjects | Zendy

Manoj Jain | Zendy; Gunjan Jain | Zendy

Open Access

Assessment of Inﬂammatory Markers IL- 6 and TNF- Alpha in Newly Diagnosed Type II Diabetics without Hypertension in Comparison with Non-Diabetic Normotensive Subjects

Author(s) -

Manoj Jain,

Gunjan Jain

Publication year - 2020

Publication title -

academia journal of medicine

Language(s) - English

Resource type - Journals

eISSN - 2663-8290

pISSN - 2663-8282

DOI - 10.47008/ajm.2020.3.2.8

Subject(s) - medicine , glycated hemoglobin , diabetes mellitus , type 2 diabetes mellitus , interleukin 6 , alpha (finance) , tumor necrosis factor alpha , gastroenterology , endocrinology , significant difference , type 2 diabetes , cytokine , surgery , construct validity , patient satisfaction

Background: The present study was conducted to assess inflammatory markers IL- 6 and TNF- alpha in newly diagnosed type II diabetics without hypertension. Subjects and Methods: 68 types of II diabetes mellitus patients and equal numbers of normotensive non-diabetic subjects were also recruited. Glycated hemoglobin (HbA1c) levels, TNF- alpha and IL- 6 were determined. Results: The mean IL- 6 level in group I was 17.4 pg/ml and in group II was 4.2 pg/ml. TNF- alpha level in group I was 35.8 pg/ml and in group II was 12.5 pg/ml. The difference was significant (P< 0.05). Conclusion: TNF- alpha and IL- 6 level was higher among diabetic patients as compared to healthy normotensive non-diabetic subjects.

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