Open AccessPROTEIN AND PEPTIDE BASED DRUG DELIVERY: PHARMACEUTICAL APPROACHES
Author(s) -
Namrata Patel,
Amresh Gupta,
Avtar Singh,
Nitish Kumar,
Mohd. Aqil Siddiqui
Publication year - 2021
Publication title -
international journal of indigenous herbs and drugs
Language(s) - English
Resource type - Journals
ISSN - 2456-7345
DOI - 10.46956/ijihd.vi.131
Subject(s) - peptide , buccal administration , drug delivery , transdermal , amino acid , chemistry , drug , pharmacology , biochemistry , medicine , organic chemistry
Protein and peptide are last three decades therapeutic peptides and proteins have risen in prominence as potential drug of future. Polymers of protein consist of amino acids covalently linked by peptide bonds. Peptides are small proteins composed of up to a couple of dozen amino acids proteins are rapidly degraded by digestive enzymes. Till recently, injections remain the foremost common means for administering these protein and peptide drugs. In the other routes that have been tried with varying degrees of success are the oral, buccal, intranasal, pulmonary, transdermal, ocular and rectal. In this review, the aim is to specialise in the varied routes and approaches for delivery of Peptide and protein drugs. The Continuous efforts are focussed for formulation of this therapeutics into safe and effective delivery systems. In this review briefly describes the possible methods for the delivery of protein and peptide drugs through various routes.