Open AccessReadiGraft BLX Putty and ReadiGraft Bone Chips in the Treatment of Severe Osteoarthropathy in Hemodialysed Patient.
Publication year - 2020
Language(s) - English
DOI - 10.46940/scmcrj.02.1005
Subject(s) - spinal osteoarthropathy , medicine , hemodialysis , continuous ambulatory peritoneal dialysis , amyloidosis , hypertrophic osteoarthropathy , beta 2 microglobulin , carpal tunnel syndrome , hemofiltration , carpal bones , surgery , wrist , pathology
Osteoarticular complications are a major concern in patients treated with long-term hemodialysis, hemofiltration or continuous ambulatory peritoneal dialysis. Uremic chronic patients, treated for long periods of time (≥15 years) with hemodialysis, could develop a new kind of osteoarthropathy due to amyloidosis characterized by abnormal distribution of beta-2 microglobulin (B2M) in joint tissue. Deposits of B2M are responsible for several lesions, clinically evident in different pathologies, such as: carpal tunnel syndrome, spondylarthrosis, and hemodialysis osteoarthropathy.