Open AccessBADAI SITOKIN COVID-19
Author(s) -
Sumihar M. R. Pasaribu
Publication year - 2021
Publication title -
majalah ilmiah methoda
Language(s) - English
Resource type - Journals
eISSN - 2656-6931
pISSN - 2088-9534
DOI - 10.46880/methoda.vol11no3.pp224-230
Subject(s) - ards , cytokine storm , proinflammatory cytokine , covid-19 , pneumonia , pandemic , acute respiratory distress , medicine , respiratory tract , intensive care medicine , immunology , virology , lung , respiratory system , inflammation , infectious disease (medical specialty) , outbreak , disease
COVID-19 is a rapidly spreading global threat that has been declared a pandemic by WHO. COVID-19 is transmitted through droplets or direct contact and infects the respiratory tract causing pneumonia in most cases and acute respiratory distress syndrome (ARDS) in about 15% of cases. Deaths in COVID-19 patients have been linked to so-called "cytokine storms" caused by the virus. Overproduction of proinflammatory cytokines leads to worsening of ARDS and extensive tissue damage resulting in multi-organ failure and death. Suppressing cytokines during the management of COVID-19 patients can increase survival rates and reduce mortality.