Open AccessCYCLIN D1: As a Risk of Breast Cancer
Author(s) -
Preeti Chauhan,
Palki Sahib Kaur,
Arockia Babu
Publication year - 2020
Publication title -
cgc international journal of contemporary technology
Language(s) - English
Resource type - Journals
ISSN - 2582-0486
DOI - 10.46860/cgcijctr.2020.12.26.134
Subject(s) - breast cancer , cyclin d1 , oncology , disease , medicine , cancer , colorectal cancer , genotype , cancer research , cell cycle , gene , biology , genetics
Breast cancer is varying group of tumors in terms of disease prognosis. Breast cancer is found as second main cause of death related with cancer. Cyclin D1 (CCND1) is an important regulator of cell cycle. CCND1over expressed in various human cancers like head, oesophageal, neck, squamous, colon, breast, prostateetc. Many studies have conducted to find correlation between polymorphism in CCND1 gene and development of breast cancer. Some studies found certain genotypes related with risk of breast cancer development. Some studies also proposed the role of varying genetic backgrounds in breast cancer development. This review focuses on role of CCND1 polymorphism and possible risk factors associated with breast cancer, which may explicate the breast cancer screening, prevention, and treatments strategies for future use.