Open AccessUTICAJ pH VREDNOSTI NA ANTIRADIKALSKI KAPACITET 4,7- DIHIDROKSIKUMARINA
Author(s) -
Žiko Milanovic,
A. Kesic,
Edina Avdović,
Jelena Đorovic Jovanovic,
Dejan Milenković
Publication year - 2021
Publication title -
zbornik radova
Language(s) - English
Resource type - Conference proceedings
eISSN - 2584-6159
pISSN - 0350-8552
DOI - 10.46793/sbt26.481m
Subject(s) - radical , chemistry , base (topology) , molar ratio , nuclear chemistry , inorganic chemistry , catalysis , organic chemistry , mathematics , mathematical analysis
The mechanisms of antiradical activity of 4,7-dihydroxycoumarin against peroxy (HOO•) radical were investigated. For this purpose were used sophisticated computational methods. Investigation was performed in the water, at different pH values (0-14). Acid-base species, which are represented in diverse molar fraction (f) at different pH values, contribute to a comprehensive examination of antiradical capacity. An overall rate constant (koverall) of the favorable reaction pathways (HAT and RAF) of 2.07×102 M-1s-1 at physiological pH indicates a moderate ability to neutralization HOO• radicals. A value of 1.05×103 M-1 s-1 occurring at pH > 10 indicates a maximum antiradical capacity of 4,7-dihydroxymumarin against the HOO• radical.