Open AccessProtective Effect of Aerobic Physical Training on Oxidative Stress Caused by Particulate Matter in Rats
Author(s) -
Victória Branca Moron,
Aline Belem Machado,
Samanta Cristina Siebel de Moraes,
Kalinkaluei Aparecida Rigo,
Micaela da Silva Constante,
Cássia Cinara da Costa,
Magda Susana Perassolo,
Daniela Montanari Migliavacca Osório,
Gustavo Roese Sanfelice,
Daiane Bolzan Berlese
Publication year - 2020
Publication title -
lecturas educación física y deportes
Language(s) - English
Resource type - Journals
ISSN - 1514-3465
DOI - 10.46642/efd.v25i270.1543
Subject(s) - oxidative stress , catalase , antioxidant , superoxide dismutase , glutathione peroxidase , particulates , chemistry , aerobic exercise , biochemistry , medicine , organic chemistry
Particulate matter (PM) is an atmospheric pollutant associated with many deleterious health effects. Oxidative stress is among these effects, that can result from a local inflammatory response to systemic damage to the organism. Studies indicate that when an individual is submitted to aerobic physical training, it generates an antioxidant protective effect that overcomes the damages caused by PM. Objective: Therefore, the aim of this study was to evaluate the influence of the particulate matter PM2.5 and PM10 on the oxidative stress parameters. Methods: The evaluation of the influence of PM on oxidative stress parameters was performed by the dosages of superoxide dismutase, catalase, glutathione peroxidase, and total antioxidant power in male Wistar rats not exposed to the particulate matter, with and without aerobic physical training, and exposed to PM2.5 and PM10, with and without aerobic physical training. This protocol lasted five weeks. Results: The antioxidant enzymes analyzed that presented significant differences were catalase, and glutathione peroxidase. Conclusions: From this research, it was possible to perceive that PM influences negatively on the oxidative stress and in the weight of the rats and that the aerobic exercise generates a protective effect against these damages.