Open AccessForearm Compartment Syndrome in a Two-year-old Boy with Severe Hemophilia A and High Titer Inhibitor Factor VIII: A Case Report
Author(s) -
Toshio Sato,
Sasa Masuo,
T. Arai,
N. Hisateru
Publication year - 2018
Publication title -
journal of clinical cases and reports
Language(s) - English
Resource type - Journals
ISSN - 2582-0435
DOI - 10.46619/joccr.2018.1-1018
Subject(s) - medicine , fasciotomy , forearm , compartment (ship) , surgery , titer , contracture , anesthesia , adverse effect , immunology , oceanography , antibody , geology
We present a case of a two-year-old boy with hemophilia A and high titer factor inhibitor, who developed forearm compartment syndrome two days after taking blood samples for a regular check-up of serum concentration of Factor VIII. Emergency fasciotomy was performed to prevent Volkmann contracture. The patient needed bypass therapies including recombitant activated factor VII (rFVIIa), activated prothrombin complexes (aPCC), factors VII・X (MC7-10), and transfusions. Eleven days after the surgical intervention, he was discharged without any functional loss in the affected upper extremity. Early surgical intervention prevented compartment syndrome of affected upper extreme.