Open AccessFunction Prediction of Human Proteins
Author(s) -
Prashansa Roy Bhavesh Tanawala and Hetal Gaudani
Publication year - 2020
Publication title -
international journal of modern trends in science and technology
Language(s) - English
Resource type - Journals
ISSN - 2455-3778
DOI - 10.46501/ijmtst061111
Subject(s) - computer science , sort , function (biology) , biological data , feature selection , human proteins , protein sequencing , protein function prediction , artificial intelligence , feature (linguistics) , protein function , machine learning , computational biology , data mining , bioinformatics , peptide sequence , biology , biochemistry , information retrieval , linguistics , philosophy , evolutionary biology , gene
Due to the rapidness in research, accumulation of biological data is happening at an overwhelming rate.Advanced computation techniques are required to gather the useful information from this enormous amountof protein data such that the knowledge is practically useful and easily interpretable. For instance, drugdiscoverers need biological or computational methods to predict the functions of proteins, responsible fordifferent sort of diseases in human body. Since traditional biological methods were time consuming andcomparatively expensive, various computational methods have been introduced in the respective researchareas. In this project, we have tried to generate machine learning models that predict the protein function ofunknown proteins and analyze their performance to get a model with highest accuracy. Protein function'ssequence annotations such as Amino Acid modifications, Molecule Processing and other structural featureslike Active Site, Beta strand, Chain, etc. along with it even protein mass and length are considered forprediction of protein functions. To further improve the accuracy feature selection has been performed.According to the enzyme nomenclature scheme the protein are classified into 6 groups. This enzyme classesis nothing but the crystalize reactions of proteins and shows the functions of it.