Open AccessDoes the frailty phenotype at the age of 66 to 71 predict death? A 14-year survival analysis of the Lc65+ study
Author(s) -
Sarah Fustii,
Brigitte Santos-Eggimann,
Yves Henchoz
Publication year - 2021
Publication title -
schweizerische medizinische wochenschrift
Language(s) - English
Resource type - Journals
ISSN - 0036-7672
DOI - 10.4414/smw.2021.w30042
Subject(s) - medicine , gerontology , proportional hazards model , cohort , survival analysis , demography , population , psychological intervention , socioeconomic status , environmental health , psychiatry , sociology
Frailty is a health characteristic resulting from the loss of physiological reserve of multiple organs, leading to exposure to adverse outcomes, and is possibly reversible in its earliest stages. It is identified by a specific phenotype that contributes to the practice of geriatric medicine, where it is considered a potential target for preventive action. This phenotype has recently attracted interest in other medical specialties for risk assessment before stressful interventions in older adults. Whereas frailty is unusual in sexagenarians, pre-frailty is common. This longitudinal study aimed to evaluate the significance of fulfilling at least one criterion of the frailty phenotype in the late sixties as a predictor of short- and long-term mortality in males and females.