Open AccessEpigenetic alteration to activate Bmp2-Smad signaling in Raf-induced senescence
Author(s) -
Mai Fujimoto,
Yasunobu Mano,
Motonobu Anai,
Shozo Yamamoto,
Masaki Fukuyo,
Hiroyuki Aburatani,
Atsushi Kaneda
Publication year - 2016
Publication title -
world journal of biological chemistry
Language(s) - English
Resource type - Journals
ISSN - 1949-8454
DOI - 10.4331/wjbc.v7.i1.188
Subject(s) - senescence , gene knockdown , biology , microbiology and biotechnology , chromatin immunoprecipitation , downregulation and upregulation , smad , gene expression , signal transduction , gene , genetics , promoter
To investigate epigenomic and gene expression alterations during cellular senescence induced by oncogenic Raf.