Open AccessHigh levels of homocysteine downregulate apolipoprotein E expressionvianuclear factor kappa B
Author(s) -
Violeta Georgeta Trusca,
Adina D Mihai,
Elena Valeria Fuior,
Ioana Mădălina Fenyo,
Anca Violeta Gafencu
Publication year - 2016
Publication title -
world journal of biological chemistry
Language(s) - English
Resource type - Journals
ISSN - 1949-8454
DOI - 10.4331/wjbc.v7.i1.178
Subject(s) - chromatin immunoprecipitation , microbiology and biotechnology , apolipoprotein e , nfat , promoter , hek 293 cells , western blot , reporter gene , transfection , transcription factor , gene expression , activator (genetics) , biology , chemistry , gene , biochemistry , medicine , disease
To investigate the effect of high homocysteine (Hcy) levels on apolipoprotein E (apoE) expression and the signaling pathways involved in this gene regulation.