Open AccessEngineered magnetic core shell nanoprobes: Synthesis and applications to cancer imaging and therapeutics
Author(s) -
Samir Mandal,
Keya Chaudhuri
Publication year - 2016
Publication title -
world journal of biological chemistry
Language(s) - English
Resource type - Journals
ISSN - 1949-8454
DOI - 10.4331/wjbc.v7.i1.158
Subject(s) - magnetic hyperthermia , magnetic nanoparticles , drug delivery , nanotechnology , targeted drug delivery , nanoparticle , cancer therapy , medicine , shell (structure) , magnetic core , materials science , cancer , engineering , electrical engineering , composite material , electromagnetic coil
Magnetic core shell nanoparticles are composed of a highly magnetic core material surrounded by a thin shell of desired drug, polymer or metal oxide. These magnetic core shell nanoparticles have a wide range of applications in biomedical research, more specifically in tissue imaging, drug delivery and therapeutics. The present review discusses the up-to-date knowledge on the various procedures for synthesis of magnetic core shell nanoparticles along with their applications in cancer imaging, drug delivery and hyperthermia or cancer therapeutics. Literature in this area shows that magnetic core shell nanoparticle-based imaging, drug targeting and therapy through hyperthermia can potentially be a powerful tool for the advanced diagnosis and treatment of various cancers.