Open AccessJAK3 inhibitor VI is a mutant specific inhibitor for epidermal growth factor receptor with the gatekeeper mutation T790M
Author(s) -
Naoyuki Nishiya
Publication year - 2015
Publication title -
world journal of biological chemistry
Language(s) - English
Resource type - Journals
ISSN - 1949-8454
DOI - 10.4331/wjbc.v6.i4.409
Subject(s) - t790m , gefitinib , autophosphorylation , tyrosine kinase inhibitor , egfr inhibitors , tyrosine kinase , epidermal growth factor receptor , cancer research , kinase , microbiology and biotechnology , chemistry , biology , biochemistry , protein kinase a , signal transduction , receptor , cancer , genetics
To identify non-quinazoline kinase inhibitors effective against drug resistant mutants of epidermal growth factor receptor (EGFR).
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