Open AccessGelatin degradation assay reveals MMP-9 inhibitors and function of O-glycosylated domain
Author(s) -
Jennifer Vandooren
Publication year - 2011
Publication title -
world journal of biological chemistry
Language(s) - English
Resource type - Journals
ISSN - 1949-8454
DOI - 10.4331/wjbc.v2.i1.14
Subject(s) - high throughput screening , gelatin , matrix metalloproteinase , chemistry , substrate (aquarium) , enzyme , mutant , biochemistry , microbiology and biotechnology , biology , gene , ecology
To establish a novel, sensitive and high-throughput gelatinolytic assay to define new inhibitors and compare domain deletion mutants of gelatinase B/matrix metalloproteinase (MMP)-9.
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