Open AccessTenascin C upregulates interleukin-6 expression in human cardiac myofibroblastsviatoll-like receptor 4
Author(s) -
Azhar Maqbool,
Emma J. Spary,
Iain W. Manfield,
Michaela Ruhmann,
Lorena Zuliani-Alvarez,
Filomena O Gamboa-Esteves,
Karen E. Porter,
Mark J. Drinkhill,
Kim S. Midwood,
Neil A. Turner
Publication year - 2016
Publication title -
world journal of cardiology
Language(s) - English
Resource type - Journals
ISSN - 1949-8462
DOI - 10.4330/wjc.v8.i5.340
Subject(s) - western blot , microbiology and biotechnology , mmp3 , tenascin c , medicine , fibronectin , matrix metalloproteinase , messenger rna , receptor , interleukin , tlr4 , recombinant dna , immunohistochemistry , gene expression , immunology , biology , cytokine , extracellular matrix , gene , biochemistry
To investigate the effect of Tenascin C (TNC) on the expression of pro-inflammatory cytokines and matrix metalloproteinases in human cardiac myofibroblasts (CMF).