Open AccessBone morphogenetic protein-4 and transforming growth factor-beta1 mechanisms in acute valvular response to supra-physiologic hemodynamic stresses
Author(s) -
Ling Sun,
Philippe Sucosky
Publication year - 2015
Publication title -
world journal of cardiology
Language(s) - English
Resource type - Journals
ISSN - 1949-8462
DOI - 10.4330/wjc.v7.i6.331
Subject(s) - paracrine signalling , noggin , medicine , transforming growth factor , bone morphogenetic protein , ex vivo , extracellular matrix , bone morphogenetic protein 2 , microbiology and biotechnology , endocrinology , in vivo , chemistry , biology , in vitro , biochemistry , receptor , gene
To explore ex vivo the role of bone morphogenetic protein-4 (BMP-4) and transforming growth factor-beta1 (TGF-β1) in acute valvular response to fluid shear stress (FSS) abnormalities.