Open AccessCoronary spasm-related acute myocardial infarction in a patient with essential thrombocythemia
Author(s) -
Chi-Wen Cheng,
MingJui Hung
Publication year - 2011
Publication title -
world journal of cardiology
Language(s) - English
Resource type - Journals
ISSN - 1949-8462
DOI - 10.4330/wjc.v3.i8.278
Subject(s) - medicine , cardiology , myocardial infarction , coronary vasospasm , essential thrombocythemia , chest pain , vasospasm , coronary artery disease , coronary thrombosis , acute coronary syndrome , artery , thrombosis , discontinuation , right coronary artery , angina , platelet , coronary angiography , subarachnoid hemorrhage
We report a case of essential thrombocythemia (ET) in a 30-year-old female who exhibited inferior wall ST-elevation acute myocardial infarction (AMI) without significant obstructive coronary artery disease. Right coronary vasospasm was observed after intra-coronary methylergonovine administration and she received verapamil 120 mg/dthereafter and hydroxyurea 1500 mg/d for thrombocythemia. After discontinuation of the hydroxyurea for 9 mo based on the impression of coronary spasm-related instead of coronary thrombosis-related AMI, her platelet count rose but no chest pain was observed. It is suggested that coronary spasm potentially plays a role in patients with ET, AMI and no significant coronary artery stenosis.