Open AccessCurrent tecniques and new perpectives research of magnetic resonance enterography in pediatric Crohn’s disease
Author(s) -
Gabriele Masselli,
Ilaria Mastroiacovo,
Emidio De Marco,
Giulia Francione,
Emanuele Casciani,
E Polettini,
Gianfranco Gualdi
Publication year - 2016
Publication title -
world journal of radiology
Language(s) - English
Resource type - Journals
ISSN - 1949-8470
DOI - 10.4329/wjr.v8.i7.668
Subject(s) - medicine , crohn's disease , radiology , disease , magnetic resonance imaging , ionizing radiation , inflammatory bowel disease , biopsy , ulcerative colitis , pathology , irradiation , physics , nuclear physics
Crohn's disease affects more than 5 individuals in the United States, and about 25% of cases are diagnosed during the pediatric period. Imaging of the bowel has undergone dramatic changes in the past two decades. The endoscopy with biopsy is generally considered the diagnostic reference standard, this combination can evaluates only the mucosa, not inflammation or fibrosis in the mucosa. Actually, the only modalities that can visualize submucosal tissues throughout the small bowel are the computed tomography (CT) enterography (CTE) with the magnetic resonance enterography (MRE). CT generally is highly utilized, but there is growing concern over ionizing radiation and cancer risk; it is a very important aspect to keep in consideration in pediatric patients. In contrast to CTE, MRE does not subject patients to ionizing radiation and can be used to detect detailed morphologic information and functional data of bowel disease, to monitor the effects of medical therapy more accurately, to detect residual active disease even in patients showing apparent clinical resolution and to guide treatment more accurately.