Open AccessRadiogenomic imaging-linking diagnostic imaging and molecular diagnostics
Author(s) -
Mathias Goyen
Publication year - 2014
Publication title -
world journal of radiology
Language(s) - English
Resource type - Journals
ISSN - 1949-8470
DOI - 10.4329/wjr.v6.i8.519
Subject(s) - radiogenomics , medicine , molecular imaging , cancer imaging , medical imaging , computational biology , medical physics , pathology , radiomics , radiology , cancer , biology , microbiology and biotechnology , in vivo
Radiogenomic imaging refers to the correlation between cancer imaging features and gene expression and is one of the most promising areas within science and medicine. High-throughput biological techniques have reshaped the perspective of biomedical research allowing for fast and efficient assessment of the entire molecular topography of a cell's physiology providing new insights into human cancers. The use of non-invasive imaging tools for gene expression profiling of solid tumors could serve as a means for linking specific imaging features with specific gene expression patterns thereby allowing for more accurate diagnosis and prognosis and obviating the need for high-risk invasive biopsy procedures. This review focuses on the medical imaging part as one of the main drivers for the development of radiogenomic imaging.