Mean Platelet Volume in Patients with Chronic Hepatititis B

Aim: Hepatitis B virus infection is a major public health problem. Hepatitis B Liver biopsy is the gold standard procedure for documenting liver damage in chronic hepatitis.Many noninvassive tests have been studied for the determining the liver damage. We aimed this study to evaluate the role of mean platelet volume (MPV) as a fibrosis marker in patients with chronic hepatitis B. Material and Method: Thirty three patients with Chronic hepatitis B(CHB) were enrolled retrospectively into the study and 37 healthy subjects were used as control group. Patient with CHB infection were divided into two groups:patients with fibrosis score 0-3 and 4-6. Data were obtained from the patients files and a computerized database. Results:The mean age of the patients with CHB was 35.62±14.62 and the control group was 39.24±13.01. The mean platelet volume was 8.95±0.50 in CHB group and 8.67±0.57 in the control group.There was a statiscically significant difference between the groups(