Research for the Agents of the Urinary Infection Resistant to Multiple Antibiotics and Risk Factors

Aim: In our study, we aimed to determine the risk factors of multiple antibiotics resistant urinary system infections which are found in urology clinics. Material and Method: In this study, 255 cases in Izmir Bozyaka Education and Research Hospital Urology clinic from January 2007 to December 2009 in whose urine cultures urinary infection agents (multi-drug resistance bacteria) have grown, were investigated and the patient files were examined retrospectively. The patients whose asymptomatic bacteriuria in culture samples was accepted as contamination or the ones with asymptomatic candiduria or the ones younger than 18 were not included. Results: From their urine cultures, 255 multiple resistant microorganisms were isolated. In 219 of the cultures gram negative (86%) and in 36 (14%) gram positive agents were isolated. The mean age of the cases accepted to the study was 69 (between 18 and 82). 66% of the cases were male, 34% were female. Most of the patients histories were significant with several urological diagnoses (Benign prostatic hyperplasia, urinary tract stone disease etc.) In more than half of the cases, there was a history of urinary tract infection diagnosed in the last six months (71%); and there was antibiotic use history in 86% of the patients in the last six months. In 89% of the patients urinary catheter was applied. The mostly applied catheterizations to patients were bladder catheterization with 81%. Discussion: In our study, all the patients who have got multiple antibiotic resistances in their urine cultures, had at least two of followings: Frequent hospital admissions and hospitalization, urinary catheterization and repeated urological surgical intervention history. We found out existence of urinary catheter and recent use of antibiotics, as the highest risk factor for resistant urinary infection development