Open AccessHigh frequency of BRAF V600E mutation in Iranian population ameloblastomas
Author(s) -
Samira Derakhshan,
Pouyan Aminishakib,
Abbas Karimi,
Hiva Saffar,
Amir Abdollahi,
Hadiseh Mohammadpour,
M-J Kharazi Fard,
A Memarha
Publication year - 2020
Publication title -
medicina oral, patología oral y cirugía bucal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 56
eISSN - 1698-6946
pISSN - 1698-4447
DOI - 10.4317/medoral.23519
Subject(s) - ameloblastoma , mutation , immunohistochemistry , medicine , pathology , population , v600e , monoclonal antibody , polymerase chain reaction , cancer research , antibody , biology , gene , immunology , genetics , dentistry , maxilla , environmental health
Ameloblastoma is a common locally invasive but slow-growing neoplasm of the jaws with an odontogenic origin. Association between BRAF V600E mutation and clinicopathologic features and behavior of ameloblastoma remains controversial. This study aimed to evaluate BRAF V600E gene mutation and expression of its related proteins with clinicopathologic parameters in conventional ameloblastoma.