Tomographic study of Jaw bone changes in patients with bisphosphonate-related osteonecrosis | Zendy

Guilherme Simpione | Zendy; R. J. Caldas | Zendy; MQ. Soares | Zendy; Izabel Regina Fischer RubiraBullen | Zendy; PS. Santos | Zendy

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Tomographic study of Jaw bone changes in patients with bisphosphonate-related osteonecrosis

Author(s) -

Guilherme Simpione,

R. J. Caldas,

MQ. Soares,

Izabel Regina Fischer RubiraBullen,

PS. Santos

Publication year - 2020

Publication title -

journal of clinical and experimental dentistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.481

H-Index - 23

ISSN - 1989-5488

DOI - 10.4317/jced.56265

Subject(s) - medicine , osteonecrosis of the jaw , bisphosphonate , bisphosphonate associated osteonecrosis of the jaw , dentistry , osteoporosis , mandible (arthropod mouthpart) , zoledronic acid , radiology , botany , biology , genus

Bisphosphonates (BP) are synthetic pyrophosphate-like substances with antiresorptive properties and specifically affect osteoclastic activity. In 2007, the American Association of Oral and Maxillofacial Surgeons (AAOMS) defined diagnostic criteria for Osteonecrosis of the Jaws Associated with Bisphosponates (BRONJ). BRONJ is mainly diagnosed by clinical features, but the detection of early bone changes by imaging may help prevent and better understand the disease. The objective of this study was to evaluate maxillary changes in CBCT in patients using BP.

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