Open AccessSquamous cell carcinoma related with dental implants. A clinical cases report
Author(s) -
F. Granados,
Leonor Santos-Ruíz,
M. Contreras,
J. Mellado,
G. Martin,
L. Bermudo,
F. Ruiz,
Y. Aguilar,
I. Yáñez
Publication year - 2020
Publication title -
journal of clinical and experimental dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.481
H-Index - 23
ISSN - 1989-5488
DOI - 10.4317/jced.55964
Subject(s) - basal cell , dentistry , medicine , oncology , pathology
One third of all cases of head and neck carcinoma (CA) concern the oral mucosa. The use of dental implants (DI) for dental rehabilitation is widely extended. However, a few studies have reported some cases with neoplasic alterations, among the tissue surrounding implants. Our aim was to analyze possible alterations at the bone-implant interface in patients with oral squamous cell carcinoma (SCC), providing new evidence that could relate or discard a possible link between these factors. We used, for the first time, different techniques, including electron microscopy and histology, to analyze the implant ´s surface and the surrounding tissue from four clinical cases with neoplasic alterations surrounding DI. Histologically, ample inflammatory tissue was found in direct contact with the implant surface. Surface analysis of this tissue, revealed titanium percentages. According to our study, no oncological relation with deterioration of the implant surface was found, although DI were constantly related with peri-implantitis, a chronic trauma of the oral mucosa that could involve a neoplastic factor. Key words: Dental implants, carcinoma, peri-implantitis.