Open AccessVitamin D associated inflammation and atherosclerosis
Author(s) -
Seetha Munisamy,
Sitisafiah Mokhtar,
Low Jen Hou,
Wee Chee Lee,
Aida Hanum Ghulam Rasool
Publication year - 2022
Publication title -
tropical journal of pharmaceutical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.209
H-Index - 36
eISSN - 1596-5996
pISSN - 1596-9827
DOI - 10.4314/tjpr.v20i7.30
Subject(s) - inflammation , vitamin d and neurology , pathogenesis , medicine , immunology , inflammatory response
Vitamin D is known to play a crucial role in mineral homeostasis and bone metabolism. Recent discoveries showed that the vitamin also regulate the inflammatory mediators. A number of studies have reported on the association of low vitamin D levels with increased level of inflammatory parameters; which predisposes to atherosclerosis and development of cardiovascular diseases (CVD). Since inflammation is implicated in the pathogenesis of CVD, measurement of inflammatory marker levels has been proposed as a method to improve the prediction of these events. In this review, the mechanism of inflammation and role of vitamin D in combating inflammation are discussed