Open AccessUncaria gambir (W. Hunter) Roxb: From phytochemical composition to pharmacological importance
Author(s) -
Mohd Zuwairi Mat Saad,
Hoe-Han Goh,
Roslee Rajikan,
Tengku Roslina Tuan Yusof,
Syarul Nataqain Baharum,
Hamidun Bunawan
Publication year - 2020
Publication title -
tropical journal of pharmaceutical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.209
H-Index - 36
eISSN - 1596-5996
pISSN - 1596-9827
DOI - 10.4314/tjpr.v19i8.28
Subject(s) - traditional medicine , phytochemical , phytochemistry , medicine
Purpose: To present an overview of the ethnopharmacology, phytochemistry, and pharmacological effects of the ‘wonder’ plant, Uncaria gambir (W. Hunter) Roxb.Methods: The literature search for information on phytochemical composition and pharmacological importance of U. gambir was undertaken using diverse electronic search engines, including Google, Scopus, Web of Science, scientific literature, and databases (Pubmed, Springer and Science Direct). Other relevant literature sources include books, book chapters, conference papers, theses, and other scientific publications.Results: Uncaria gambir Roxb possesses significant medicinal potentials as an antioxidant, anthelmintic, antibacterial, anti-diabetic, and for the management of osteoarthritis. Interest has increased among researchers for the utilization of this plant in complementary medicine, for example, to relieve sore throat, spongy gum, and dysentery, to treat atherosclerosis and obesity, and to prolong sexual intercourse.Conclusion: Uncaria gambir demonstrates significant pharmacological properties. This review will be useful for prospective research and development of this ethnomedicinal plant into potentially valuable health products.
Keywords: Anthelmintic, Antibacterial,Anti-Diabetic, Osteoarthritis, Uncaria gambir