Open AccessMeta-analysis of effectiveness of traditional Chinese medicine or its combination with Western medicine in the treatment of triple negative breast cancer
Author(s) -
Yukun Wang,
Yao Chang,
Fan He,
Zeng Jiayao
Publication year - 2021
Publication title -
tropical journal of pharmaceutical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.209
H-Index - 36
eISSN - 1596-5996
pISSN - 1596-9827
DOI - 10.4314/tjpr.v18i3.28
Subject(s) - triple negative breast cancer , medicine , traditional chinese medicine , meta analysis , randomized controlled trial , western medicine , traditional medicine , breast cancer , alternative medicine , oncology , chinese science , cancer , pathology
Purpose: To assess the efficacy and side effects of Traditional Chinese Medicine (TCM) in the management of triple negative breast cancer (TNBC).
Methods: Full text data on randomized controlled trial (RCT) of TNBC treated with TCM or its combination with Western Medicine (WM) were retrieved from the Chinese biomedical literature database, Chinese periodicals, Chinese Science-Technology periodicals and VP and PubMed. The qualities of the RCTs were evaluated. Revman 5.3 was used to conduct the meta-analysis.
Results: A total of 16 RCTs involving 1186 patients were included. Analysis of these RCTs showed significant differences in total effectiveness between WM and TCM or combination of TCM with WM {(OR = 2.63, 95 % CI = 1.37, 5.03), test of the combined effect (Z = 2.91, p ˂ 0.005)}.
Conclusion: The results show that TCM is effective in the treatment TNBC