Open AccessSerum C-Reactive Protein in Nigerians With Type 2 Diabetes Mellitus
Author(s) -
Marycelin Baba,
Babatope Kolawole,
Rosemary Ikem,
FA Arogundade,
H Yusuph,
Ibrahim Gezawa
Publication year - 2010
Publication title -
nigerian journal of medicine/the nigerian journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 2667-0526
pISSN - 1115-2613
DOI - 10.4314/njm.v19i4.69784
Subject(s) - medicine , c reactive protein , diabetes mellitus , nigerians , myocardial infarction , risk factor , type 2 diabetes mellitus , type 2 diabetes , disease , framingham risk score , gastroenterology , endocrinology , inflammation , political science , law
C-reactive protein is an acute-phase proteins, produce in the liver, its release is stimulated by cytokines (interleukin 6 and tumour necrosis factor alpha). Elevated level of it is a risk factor for coronary heart disease. Baseline levels of C-reactive protein in apparently healthy men and women predict long-term risk of a first myocardial infarction. Diabetics are at increased risk for coronary heart disease, data from the Framingham Study showed a two- to three-fold elevation in the risk of clinically evident atherosclerotic disease in patients with type II diabetes compared to those without diabetes. However, but data regarding CRP in Nigerian diabetic is lacking.