Open AccessPrevalence of Anaemia in HIV-Infected Children at the University of Abuja Teaching Hospital, Gwagwalada
Author(s) -
Okechukwu Aa,
D Gambo,
I.O Okechukwu
Publication year - 2010
Publication title -
nigerian journal of medicine/the nigerian journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 2667-0526
pISSN - 1115-2613
DOI - 10.4314/njm.v19i1.52480
Subject(s) - medicine , zidovudine , pediatrics , stavudine , regimen , anemia , outpatient clinic , prospective cohort study , lamivudine , trimethoprim , human immunodeficiency virus (hiv) , immunology , antibiotics , viral disease , virus , hepatitis b virus , microbiology and biotechnology , biology
Use of highly active antiretroviral therapy (HAART) has remained the only regimen potent enough to reduce viral replication in HIV-infected individuals. Its combination with cotrimoxazole has also been recommended in those with CD4% of less than 15%. The use of HAART containing zidovudine (ZDV) in combination with co-trimoxazole carries the risk of anaemia in already anaemic predisposed individuals from HIV infections, opportunistic infections, parasitic infestations, sickle cell anaemia, and malnutrition. The aim of the study is to document the effect of use of combination of HAART containing ZDV with cotrimoxazole in haemoglobin profile of HIV-infected children after one year of its administration at the University of Abuja Teaching Hospital (UATH), Gwagwalada. It is also aimed at comparing the result obtained with those on stavudine containing HAART with co-trimoxazole.