Open AccessReview Article: Malaria Vaccine: The Pros and Cons
Author(s) -
Jalal-Eddeen Abubakar Saleh,
H Yusuph,
SB Zailani,
Bayu Sakti Aji
Publication year - 2010
Publication title -
nigerian journal of medicine/the nigerian journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 2667-0526
pISSN - 1115-2613
DOI - 10.4314/njm.v19i1.52464
Subject(s) - cons , malaria , malaria vaccine , virology , medicine , psychology , immunology , computer science , plasmodium falciparum , programming language
Malaria is an important parasitic disease of humans caused by infection with a parasite of the genus Polasmodium and transmitted by female anopheles. Infection caused by P. falciparum is the most serious of all the other species (P. ovale, P. vivax and P. malariae) especially in terms of morbidity and mortality hence the reason why most of the research has been focussed on this species. The disease affects up to about 40 per cent of the world's population with around 300-500 million people currently infected and mainly in the tropics. It has a high morbidity and mortality especially in resource-poor tropical and subtropical regions with an economic fall of about US$ 12 billion annually in Africa alone.