Open AccessPhytochemical Screening and Antimicrobial Analysis of Fadogia andersonii Robyn Plant Extrac
Author(s) -
J. Nzeako,
G. I. Ndukwe,
JD Habila,
E.A. Oluwabukola,
Idaba Owoicho
Publication year - 2021
Publication title -
journal of applied science and environmental management
Language(s) - English
Resource type - Journals
eISSN - 2659-1499
pISSN - 2659-1502
DOI - 10.4314/jasem.v25i2.13
Subject(s) - phytochemical , antimicrobial , aspergillus flavus , microbiology and biotechnology , klebsiella pneumonia , biology , bacillus cereus , traditional medicine , pseudomonas aeruginosa , anthraquinones , minimum inhibitory concentration , staphylococcus aureus , cereus , proteus mirabilis , minimum bactericidal concentration , bacteria , medicine , botany , genetics
Medicinal plants extracts are now generally considered as effective medicines that play a major role in modern pharmacy. The plant Fadogia andersonii belonging to the Family Rubiaceae, which is used in ethno-medicine was studied. Preliminary phytochemical analyses of the whole plant revealed the presence of the following metabolites: Saponins, terpenes, steroids, flavonoids, tannins, alkaloids, cardiac glycosides and carbohydrates. Anthraquinones was found to be absent. Antimicrobial screening of the methanol plant’s extract carried out (in vitro) on Staphylococcus aureus, Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa, Bacillus cereus, Klebsiella pneumonia, Streptococcus pneumoniae, Streptococcus pyogenes, Candida albican and Aspergillus flavus showed that the extract has activity on the tested microorganisms. However, it showed no inhibitory effect against Escherichia coli. The extract was found to inhibit the growth of S. aureus, B. cereus, S. pyogenes and C. albican at 25mg/ml with a corresponding MBC at 50mg/ml. S.typhi and S. pneumonia were inhibited at 50mg/ml with a corresponding MBC at 100mg/ml. It also inhibited the growth of P. aeruginosa, K. pneumonia and A. flavus at 100mg/ml with a corresponding MBC at 200mg/ml. The observed antimicrobial effects were believed to be due to the presence of active principles which were detected in the phytochemical screening.
Keywords: Phytochemicals, Antimicrobials, Fadogia andersonii Robyn