Efficiency of Galanti and Guisti Method of ADA Estimation in Comparison with the Gold Standard | Zendy

Manasa Reddy Dubba | Zendy; V Ramyashree | Zendy; Harshitha SS | Zendy; Monalisa Biswas | Zendy; Revathi P Shenoy | Zendy; Varashree Bolar Suryakanth | Zendy

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Efficiency of Galanti and Guisti Method of ADA Estimation in Comparison with the Gold Standard

Author(s) -

Manasa Reddy Dubba,

V Ramyashree,

Harshitha SS,

Monalisa Biswas,

Revathi P Shenoy,

Varashree Bolar Suryakanth

Publication year - 2020

Publication title -

ethiopian journal of health sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.479

H-Index - 20

eISSN - 2413-7170

pISSN - 1029-1857

DOI - 10.4314/ejhs.v30i6.7

Subject(s) - autoanalyzer , hypoxanthine , gold standard (test) , comparability , adenosine deaminase , computer science , inosine , estimation , chromatography , medicine , statistics , mathematics , chemistry , biochemistry , adenosine , enzyme , engineering , systems engineering , combinatorics

Adenosine Deaminase, the key enzyme of purine metabolism catalyzing the irreversible hydrolytic deamination of adenosine to inosine is implicated in a varied spectrum of human diseases ranging from SCID to TB and pneumonia. Estimation of ADA offers an easy, relatively affordable and reliable diagnostic alternative and/ or adjunct (specially in a TB endemic nation) which emphasizes the necessity of a feasible and implementable alternative method to the Diazyme method of ADA estimation requiring high end autoanalyzer and infrastructural setup.

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