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Posterior mediastinal Castleman’s disease with vascular malformation
Author(s) -
Ayalew T. Tamire
Publication year - 2018
Publication title -
east and central african journal of surgery
Language(s) - English
Resource type - Journals
eISSN - 2073-9990
pISSN - 1024-297X
DOI - 10.4314/ecajs.v23i2.5
Subject(s) - medicine , thoracotomy , mediastinum , etiology , arteriovenous malformation , chest pain , vascular malformation , mediastinal mass , surgery , radiology , pathology
Castelman’s disease (CD) is a rare lymphoproliferative disorder of unknown aetiology, with the unicentric form usually involving the chest. Posterior mediastinal involvement is uncommon, exceedingly so when associated with vascular malformation. We report the case of a young female patient who presented with 9 months of left-sided, dull chest and flank pain associated with weight loss and a subjective tingling sensation. Imaging reveled a well-circumscribed hyper-enhancing posterior mediastinal para-oesophageal mass. She underwent a right posterolateral thoracotomy, mass excision. Histopathologic examination confirmed Castleman’s disease (CD) with arteriovenous malformation. CD with vascular malformation is a very rare condition that can only be diagnosed histopathologically. Surgical resection is effective and has a good prognosis. Keywords: Castleman’s disease; AV malformation; posterior mediastinum 

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